I-Microalgae ingenye yezinhlobo ezindala kakhulu eMhlabeni, uhlobo lwe-algae encane engakhula emanzini ahlanzekile nasolwandle ngesivinini esimangalisayo sokuzala. Ingasebenzisa kahle ukukhanya kanye ne-carbon dioxide ukuze i-photosynthesis noma isebenzise imithombo elula yekhabhoni ephilayo ukuze ikhule ngendlela ehlukile, futhi ikhiqize izakhamzimba ezahlukahlukene ezifana namaprotheni, ushukela, namafutha ngokusebenzisa i-metabolism yamaseli.

Ngakho-ke, ama-microalgae abhekwa njengamaseli e-chassis afanele kakhulu ekufezeni ukukhiqizwa kwezinto eziphilayo okuluhlaza nokusimeme, futhi asetshenziswe kabanzi emikhakheni ehlukahlukene njengokudla, imikhiqizo yezempilo, imithi, izimonyo, ama-biofuel, kanye nama-bioplastic.

Muva nje, inkampani yasekhaya ye-microalgae synthetic biology, i-Protoga Biotech, imemezele ukuthi iphrotheni yayo entsha ye-microalgae idlule ngempumelelo esigabeni sokukhiqiza sokuhlola, ngomthamo omkhulu wokukhiqiza wamakhilogremu angu-600 ephrotheni ngosuku. Umkhiqizo wokuqala osekelwe kuphrotheni entsha ye-microalgae, ubisi lwezitshalo ze-microalgae, nawo uphumelele ukuhlolwa kokuhlola futhi kulindeleke ukuthi wethulwe futhi uthengiswe ekupheleni kwalo nyaka.

Esebenzisa leli thuba, uShenghui waxoxa noDkt. Li Yanqun, unjiniyela oyinhloko wokuthuthukiswa kwezicelo e-protoga Biotechnology. Wethula kuShenghui imininingwane yokuhlolwa okuphumelelayo kweprotheyini ye-microalgae kanye namathuba okuthuthukiswa emkhakheni weprotheyini yezitshalo. ULi Yanqun uneminyaka engaphezu kwengu-40 yesipiliyoni somsebenzi wesayensi nobuchwepheshe emkhakheni wokudla okukhulu, ikakhulukazi ohileleke ocwaningweni nasekuthuthukisweni kwezicelo ze-microalgae biotechnology kanye ne-food biotechnology. Waphothula iziqu ze-PhD ku-Fermentation Engineering e-Jiangnan University. Ngaphambi kokujoyina i-protoga Biology, wakhonza njengoprofesa eSikoleni Sesayensi Nobuchwepheshe Bokudla, e-Guangdong Ocean University.

"Njengoba igama lenkampani lisho, i-protoga Biotechnology idinga ukusungula izinto ezintsha kusukela ekuqaleni futhi ibe nekhono lokukhula kusukela ekuqaleni. I-protoga imelela umoya oyinhloko wenkampani, okuwukuzibophezela kwethu ekusunguleni izinto ezintsha emthonjeni kanye nokuthuthukiswa kobuchwepheshe nemikhiqizo emisha yokuqala. Imfundo iwukuhlakulela nokukhula, kanti ubuchwepheshe kanye nemibono yokusungula izinto ezintsha emthonjeni kudingeka kuthuthuke kube imboni entsha, indlela entsha yokusebenzisa, ngisho nefomethi entsha yezomnotho. Sivule indlela entsha yokukhiqiza imikhiqizo enenani eliphezulu sisebenzisa i-microalgae, okuyisengezo esibalulekile ekukhiqizweni nasekuhlinzekweni kwezinsiza zokudla, ngokuhambisana nomqondo wamanje wokudla okukhulu, ngenkathi futhi kuthuthukiswa izinkinga zemvelo." ULi Yanqun utshele uShenghui.

Lobu buchwepheshe buvela eNyuvesi yaseTsinghua, bugxile ekukhuthazeni amaprotheni ezitshalo ze-microalgae
I-protoga Biotechnology yinkampani ye-biotechnology eyasungulwa ngo-2021, igxile ekuthuthukisweni nasekucutshungulweni komkhiqizo kobuchwepheshe be-microalgae. Ubuchwepheshe bayo buthathwe eminyakeni ecishe ibe ngu-30 yokuqongelela ucwaningo elabhorethri ye-microalgae yaseTsinghua University. Ulwazi lomphakathi lubonisa ukuthi selokhu yasungulwa, le nkampani iqoqe imali engaphezu kwezigidi eziyi-100 zama-yuan futhi yandisa ubukhulu bayo.

Njengamanje, isungule ilabhorethri yocwaningo nokuthuthukiswa kobuchwepheshe bebhayoloji yokwenziwa eShenzhen, isisekelo sokuhlola sokuhlola eZhuhai, ifektri yokukhiqiza eQingdao, kanye nesikhungo sokumaketha samazwe ngamazwe eBeijing, esihlanganisa izinqubo zokuthuthukiswa komkhiqizo, ukuhlolwa kokuhlola, ukukhiqiza, kanye nokuhweba.

Ngokukhethekile, ilabhorethri yocwaningo nokuthuthukiswa kobuchwepheshe bebhayoloji yokwenziwa eShenzhen igxile kakhulu ocwaningweni oluyisisekelo futhi inochungechunge oluphelele lobuchwepheshe kusukela kubunjiniyela bamaseli ayisisekelo, ukwakhiwa kwendlela ye-metabolic, ubuchwepheshe bokuhlola ukucindezeleka kuya ekuthuthukisweni komkhiqizo; Inesisekelo sokuhlola esingamamitha-skwele angu-3000 eZhuhai futhi ifakiwe ekukhiqizweni kokuhlola. Umthwalo wayo oyinhloko ukwandisa ukubiliswa nokutshalwa kwezinhlobo ze-algae noma zamabhaktheriya ezithuthukiswe yilabhorethri ye-R&D esikalini sokuhlola, futhi iqhubeke nokucubungula i-biomass ekhiqizwa ukubiliswa ibe imikhiqizo; Ifektri yaseQingdao iwumugqa wokukhiqiza wezimboni obhekene nokukhiqizwa kwemikhiqizo ngezinga elikhulu.

Ngokusekelwe kulezi zindawo zobuchwepheshe kanye nezindawo zokukhiqiza, sisebenzisa izindlela zezimboni ukuhlakulela i-microalgae nokukhiqiza izinto zokusetshenziswa ezahlukahlukene ezisuselwe ku-microalgae kanye nemikhiqizo eminingi, okuhlanganisa i-microalgae protein, i-levastaxanthin, i-microalgae exosomes, i-DHA algal oil, kanye ne-naked algae polysaccharides. Phakathi kwazo, i-DHA algal oil kanye ne-naked algae polysaccharides seziqalisiwe ukuthengiswa, kuyilapho i-microalgae protein ingumkhiqizo wethu omusha owumthombo kanye nephrojekthi eyinhloko yokukhuthaza nokukhulisa ukukhiqizwa. Eqinisweni, isikhundla esiyinhloko samaprotheni e-microalgal singabonakala nasegameni lesiNgisi elithi metazoa, elingaqondwa njengesifinyezo se-"protein of microalga"

Iphrotheni ye-microalgae iphumelele ngempumelelo ukuhlolwa kokuhlola, futhi kulindeleke ukuthi ubisi olusekelwe ezitshalweni ze-microalgae luzokwethulwa ekupheleni konyaka.
"Iphrotheni iyisakhi esibalulekile esingahlukaniswa sibe amaprotheni ezilwane kanye namaprotheni ezitshalo. Kodwa-ke, kusenezinkinga ngokunikezwa kwamaprotheni okunganele nokungalingani emhlabeni jikelele. Isizathu salokhu ukuthi ukukhiqizwa kwamaprotheni kuncike kakhulu ezilwaneni, ngokusebenza kahle kokuguqulwa okuphansi kanye nezindleko eziphakeme. Njengoba kunezinguquko emikhubeni yokudla kanye nemibono yokusebenzisa, ukubaluleka kwamaprotheni ezitshalo kuya ngokuya kugqama. Sikholelwa ukuthi amaprotheni ezitshalo, njengeprotheni entsha ye-microalgae esiyithuthukisile, inamandla amakhulu okuthuthukisa ukutholakala kwamaprotheni," kusho uLi Yanqun.

Uqhube wathi uma kuqhathaniswa nezinye, iphrotheni yesitshalo se-microalgae yenkampani inezinzuzo eziningi ekusebenzeni kahle kokukhiqiza, ukufana, ukuzinza, ukuvikelwa kwemvelo, kanye nenani lokudla okunomsoco. Okokuqala, iphrotheni yethu ye-microalgal empeleni ifana kakhulu "nephrotheni yokubilisa", okuyiphrotheni yezitshalo ekhiqizwa kusetshenziswa ubuchwepheshe bokubilisa. Ngokuphambene nalokho, inqubo yokukhiqiza yale phrotheni ebilisiwe ishesha, futhi inqubo yokubilisa ingenzeka unyaka wonke ngaphandle kokuthintwa yisizini; Ngokuphathelene nokulawulwa nokuvumelana, inqubo yokubilisa yenziwa endaweni elawulwayo, engaqinisekisa ikhwalithi nokuvumelana komkhiqizo. Ngesikhathi esifanayo, ukubikezela nokulawulwa kwenqubo yokubilisa kuphakeme, okunganciphisa ithonya lesimo sezulu nezinye izici zangaphandle; Ngokuphathelene nokuphepha, inqubo yokukhiqiza yale phrotheni ebilisiwe ingalawula kangcono ukungcola kanye namagciwane, ithuthukise ukuphepha kokudla, futhi yandise impilo yeshelufu yomkhiqizo ngobuchwepheshe bokubilisa; Iphrotheni yethu yesitshalo ebilisiwe nayo inezinzuzo zemvelo. Inqubo yokubilisa inganciphisa ukusetshenziswa kwezinsiza zemvelo ezifana nomhlaba namanzi, inciphise ukusetshenziswa komanyolo kanye nezibulala-zinambuzane ekukhiqizweni kwezolimo, futhi inciphise ukunyatheliswa kwekhabhoni kanye nokukhishwa kwamagesi okushisa.

“Ngaphezu kwalokho, inani lokudla okunempilo leprotheyini yezitshalo ze-microalgae nalo licebile kakhulu. Ukwakheka kwayo kwe-amino acid kunengqondo kakhulu futhi kuhambisana nephethini yokwakheka kwe-amino acid enconywe yi-World Health Organisation kuneyezitshalo ezinkulu ezifana nelayisi, ukolweni, ummbila, kanye nobhontshisi. Ngaphezu kwalokho, iphrotheyini yezitshalo ze-microalgae iqukethe inani elincane lamafutha, ikakhulukazi uwoyela ongagcwalisiwe, futhi ayinayo i-cholesterol, ezuzisa kakhulu ibhalansi yokudla okunempilo yomzimba. Ngakolunye uhlangothi, iphrotheyini yezitshalo ze-microalgae iqukethe nezinye izakhamzimba, okuhlanganisa ama-carotenoid, amavithamini, amaminerali asekelwe ku-bio, njalo njalo.” kusho uLi Yanqun ngokuzethemba.

UShenghui ufunde ukuthi isu lenkampani lokuthuthukisa iphrotheni ye-microalgae lihlukaniswe ngezici ezimbili. Ngakolunye uhlangothi, ukuthuthukisa izinto zokusetshenziswa ezintsha zephrotheni ye-microalgae ukuze kuhlinzekwe ngezinto zokusetshenziswa ezinkampanini ezifana nokudla, izimonyo, noma izinto eziphilayo; Ngakolunye uhlangothi, uchungechunge lwemikhiqizo ehlobene luye lwasungulwa ngokusekelwe kuphrotheni entsha ye-microalgae, okwakha i-matrix yemikhiqizo yephrotheni ye-microalgae. Umkhiqizo wokuqala ubisi lwesitshalo se-microalgae.

Kuhle ukusho ukuthi iphrotheni ye-microalgae yenkampani isanda kudlula esigabeni sokukhiqiza esivivinywayo, enomthamo wokukhiqiza ovivinywayo ongaba ngu-600 kg/ngosuku we-microalgae protein powder. Kulindeleke ukuthi yethulwe kulo nyaka. Ngaphezu kwalokho, iphrotheni ye-microalgae iphinde yadlula ekwakhiweni kwempahla yengqondo efanele futhi yafaka isicelo sochungechunge lwezimvume zokusungula izinto ezintsha. ULi Yanqun washo ngobuqotho ukuthi ukuthuthukiswa kwamaprotheni kuyisu lesikhathi eside lenkampani, futhi iphrotheni ye-microalgal iyisixhumanisi esibalulekile ekufezeni leli su. Ukuhlolwa okuphumelelayo kokuhlola kwamaprotheni e-microalgae kulokhu kuyisinyathelo esibalulekile ekufezeni isu lethu lesikhathi eside. Ukuqaliswa kwemikhiqizo emisha kuzofaka isandla ekuthuthukisweni okunempilo kwenkampani futhi kulethe amandla aqinile ekusebenzeni kwayo okuqhubekayo; Emphakathini, lokhu ukusetshenziswa komqondo womqondo wokudla okukhulu, okucebisa kakhulu izinsiza zemakethe yokudla.

Ubisi lwezitshalo luyisigaba esikhulu sokudla okusekelwe ezitshalweni emakethe, okuhlanganisa ubisi lwesoya, ubisi lwe-walnut, ubisi lwamantongomane, ubisi lwe-oat, ubisi lukakhukhunathi, kanye nobisi lwe-almond. Ubisi lwe-protoga Biology olusekelwe ezitshalweni lwe-microalgae luzoba uhlobo olusha lobisi olusekelwe ezitshalweni, okulindeleke ukuthi luqaliswe futhi luthengiswe ekupheleni kwalo nyaka, futhi luzoba ubisi lokuqala emhlabeni olusekelwe ezitshalweni lwe-microalgae oluthengiswa ngempela.

Ubisi lwesoya lunokuqukethwe okuphezulu kwamaprotheni, kodwa kukhona iphunga likabhontshisi kanye nezici ezilwa nokudla okunomsoco kuma-soya, okungathinta ukusetshenziswa kwalo ngempumelelo emzimbeni. I-oat ingumkhiqizo wokusanhlamvu onokuqukethwe okuphansi kwamaprotheni, futhi ukudla inani elifanayo lamaprotheni kuzoholela kuma-carbohydrate engeziwe. Ubisi lwezitshalo njengobisi lwe-alimondi, ubisi lukakhukhunathi, nobisi lwe-peanut lunokuqukethwe okuphezulu kwamafutha, futhi lungadla amafutha engeziwe uma lusetshenziswa. Uma kuqhathaniswa nale mikhiqizo, ubisi lwezitshalo lwe-microalgae lunokuqukethwe okuphansi kwamafutha kanye nesitashi, olunokuqukethwe okuphezulu kwamaprotheni. Ubisi lwezitshalo lwe-Microalgae oluvela ezintweni eziphilayo zakudala lwenziwa nge-microalgae, equkethe i-lutein, ama-carotenoid, namavithamini, futhi lunenani elicebile lokudla okunomsoco. Esinye isici ukuthi Ubisi olusekelwe ezitshalweni lukhiqizwa kusetshenziswa amaseli e-algae futhi lugcina izakhamzimba eziphelele, kufaka phakathi i-fiber ecebile yokudla; ​​Ngokuphathelene nokunambitheka, ubisi lwe-protein olusekelwe ezitshalweni luvame ukuba nokunambitheka okuthile okuvela ezitshalweni ngokwazo. I-microalgae yethu ekhethiwe inephunga elincane le-microalgal futhi ilawulwa ukuveza ukunambitheka okuhlukile ngobuchwepheshe obukhethekile. Ngikholwa ukuthi ubisi olusekelwe ezitshalweni olususelwa kuma-microalgae, njengohlobo olusha lomkhiqizo, luzoqhuba futhi luhole intuthuko yemboni, ngaleyo ndlela lukhuthaze intuthuko yemakethe yobisi yonke esuselwa ezitshalweni uLi Yanqun wachaza.

"Imakethe yamaprotheni ezitshalo ibhekene nethuba elihle lokuthuthuka"
Iphrotheni yezitshalo uhlobo lwephrotheni olutholakala ezitshalweni, olugaywa kalula futhi lumuncwe umzimba womuntu. Ingomunye wemithombo ebalulekile yamaprotheni okudla kwabantu futhi, njengephrotheni yezilwane, ingasekela imisebenzi eyahlukahlukene yokuphila njengokukhula komuntu kanye nokunikezwa kwamandla. Kwabadla imifino, abantu abanokungezwani namaprotheni ezilwane, kanye nezinkolelo ezithile zenkolo kanye nabezemvelo, inobungane kakhulu futhi iyadingeka.

"Ngokombono wesidingo sabathengi, izitayela zokudla okunempilo, kanye nokuphepha kokudla, isidingo sabantu sokudla okusimeme kanye namaprotheni enyama siyakhula. Ngikholwa ukuthi isilinganiso samaprotheni ezitshalo ekudleni kwabantu sizoqhubeka nokukhula, futhi isakhiwo esifanele kanye nokuhlinzekwa kwezinto zokusetshenziswa zokudla kuzophinde kushintshe kakhulu. Ngamafuphi, isidingo samaprotheni ezitshalo sizoqhubeka nokukhula esikhathini esizayo, futhi imakethe yamaprotheni ezitshalo iletha ithuba elihle lokuthuthuka," kusho uLi Yanqun.

Ngokusho kombiko weMakethe Yomhlaba Wonke we-Bussiness Research Company ka-2024, ubukhulu bemakethe yeprotheyini yezitshalo bukhule kakhulu eminyakeni yamuva nje. Ubukhulu bemakethe ngo-2024 buzokhula bufike ku-$52.08 billion, futhi kulindeleke ukuthi ubukhulu bemakethe kulo mkhakha bukhuphuke bufike ku-$107.28 billion ngo-2028, ngesilinganiso sokukhula sonyaka esihlanganisiwe esingaba ngu-19.8%.

ULi Yanqun waqhubeka wathi, “Eqinisweni, imboni yamaprotheni ezitshalo inomlando omude futhi akuyona imboni esafufusa. Eminyakeni eyishumi edlule, njengoba yonke imakethe yamaprotheni ezitshalo iba yinkimbinkimbi futhi isimo sengqondo sabantu sishintsha, iphinde yadonsela ukunaka. Kulindeleke ukuthi izinga lokukhula kwemakethe yomhlaba wonke lizosondela ku-20% eminyakeni eyi-10 ezayo.”

Kodwa-ke, uphinde wakhuluma ngokuthi yize imboni yamaprotheni ezitshalo okwamanje isesigabeni sokuthuthuka okusheshayo, kusenezinkinga eziningi okufanele zixazululwe futhi zithuthukiswe enkambisweni yokuthuthuka. Okokuqala, kunenkinga yemikhuba yokusebenzisa. Kwamanye amaprotheni ezitshalo angewona awendabuko, abathengi badinga ukuzijwayeza kancane kancane inqubo yokwamukelwa; Bese kuba nenkinga yokunambitheka kwamaprotheni ezitshalo. Amaprotheni ezitshalo ngokwawo anokunambitheka okuhlukile, okudinga nenqubo yokwamukelwa nokuqashelwa. Ngesikhathi esifanayo, ukwelashwa okufanele ngezindlela zobuchwepheshe nakho kuyadingeka esigabeni sokuqala; Ngaphezu kwalokho, kunezinkinga ngezindinganiso zomthetho, futhi njengamanje, amanye amaprotheni ezitshalo angase ahileleke ezindabeni ezifana nokuntuleka kwemithetho efanele okufanele ilandelwe.