Ukwenziwa kweAstaxanthin kwiChlamydomonas Reinhardtii

I-PROTOGA isanda kubhengeza ukuba iphumelele ekuveliseni i-astaxanthin yendalo kwi-Chlamydomonas Reinhardtii nge-Microalgae Genetic Modification Platform, kwaye ngoku iphuhlisa uphando oluhambelanayo lwepropathi yobuchwephesha kunye nophando olusezantsi. Kubikwa ukuba esi sisizukulwana sesibini seeseli zobunjineli ezibekwe kwipayipi ye-astaxanthin kwaye siza kuqhubeka nokuphindaphinda. Isizukulwana sokuqala seeseli zobunjineli singene kwinqanaba lovavanyo lovavanyo. Ukwenziwa kwe-astaxanthin kwi-Chlamydomonas Reinhardtii kwimveliso yemizi-mveliso kuya kuba ngcono ngexabiso, imveliso kunye nomgangatho kunoko kwe-Haematococcus Pluvialis.

I-Astaxanthin yi-xanthophyll yendalo neyokwenziwa kunye ne-carotenoid engeyiyo i-provitamin A, ene-antioxidant, anti-inflammatory kunye ne-antineoplastic activity. Umsebenzi wayo we-antioxidant uphindwe ka-6000 kunowe-vitamin C kwaye uphindwe ka-550 kunowe-vitamin E. I-Astaxanthin isebenza kakuhle kakhulu ekulawuleni amasosha omzimba, ukugcinwa kwenkqubo yentliziyo, impilo yamehlo nengqondo, amandla olusu, ukulwa nokwaluphala kunye nezinye izinto ezisetyenziswayo. I-Astaxanthin idla ngokusetyenziswa kwiimveliso zokhathalelo lwempilo, iimveliso zesondlo sokutya ezinefuthe lokhathalelo lwempilo kwaye yongezwa kwizithambiso ezinefuthe lokhathalelo lwempilo.

Imarike ye-astaxanthin yehlabathi kulindeleke ukuba ifikelele kwi-$2.55 yeebhiliyoni ngo-2025 ngokutsho kweGrand View Research. Okwangoku, umsebenzi we-astaxanthin ofunyenwe kwi-chemical synthesis kunye ne-Phaffia rhodozyma uphantsi kakhulu kunowe-levo-astaxanthin yendalo ephuma kwi-microalgae ngenxa yomsebenzi wayo wolwakhiwo. Yonke i-levo-astaxanthin yendalo kwimarike ivela kwi-Haematococcus Pluvialis. Nangona kunjalo, ngenxa yokukhula kwayo okucothayo, umjikelo wokukhula ixesha elide kunye nokuchaphazeleka lula ziimeko zokusingqongileyo, amandla emveliso ye-Haematococcus Pluvialis anqongophele.

Njengomthombo omtsha weemveliso zendalo kunye neseli ye-chassis yebhayoloji yokwenziwa, i-microalgae inenethiwekhi eyinkimbinkimbi ye-metabolic kunye neenzuzo ze-biosynthesis. I-Chlamydomonas Reinhardtii yi-chassis yepateni, eyaziwa ngokuba yi-"green yeast". I-PROTOGA ikwazile ukujongana netekhnoloji yokuhlela i-microalgae genetic editing ephucukileyo kunye netekhnoloji yokubilisa i-microalgae esezantsi. Kwangaxeshanye, i-PROTOGA iphuhlisa itekhnoloji ye-photoautotrophic. Nje ukuba itekhnoloji yokufuya ikhule kwaye ingasetyenziswa kwimveliso yesikali, iya kuphakamisa ukusebenza kakuhle kokwenziwa okuguqula i-CO2 ibe yimveliso esekwe kwi-bio.