ʻO ka hana ʻana o Astaxanthin ma Chlamydomonas Reinhardtii

Ua hoʻolaha koke aku nei ʻo PROTOGA ua hoʻohui pono ʻo ia i ka astaxanthin kūlohelohe ma Chlamydomonas Reinhardtii ma o ka Microalgae Genetic Modification Platform, a ke hoʻomohala nei i ka waiwai noʻonoʻo pili a me ka noiʻi hana ma hope. Ua hōʻike ʻia ʻo kēia ka hanauna ʻelua o nā cell ʻenekinia i hoʻokomo ʻia i loko o ka pipeline astaxanthin a e hoʻomau i ka hana hou. Ua komo ka hanauna mua o nā cell ʻenekinia i ke kahua hoʻāʻo hoʻāʻo. ʻOi aku ka maikaʻi o ka hoʻohui ʻana o ka astaxanthin ma Chlamydomonas Reinhardtii no ka hana ʻoihana ma ke kumukūʻai, ka huahana a me ka maikaʻi ma mua o Haematococcus Pluvialis.

He xanthophyll kūlohelohe a synthetic a me ka carotenoid nonprovitamin A ʻo Astaxanthin, me nā hana antioxidant, anti-inflammatory a me antineoplastic hiki. ʻO kāna hana antioxidant he 6000 mau manawa o ka huaora C a me 550 mau manawa o ka huaora E. He hana maikaʻi loa ʻo Astaxanthin i ka hoʻoponopono ʻana i ka pale ʻana, ka mālama ʻana i ka ʻōnaehana cardiovascular, ke olakino o ka maka a me ka lolo, ka ikaika o ka ʻili, ka anti-aging a me nā noi ʻē aʻe. Hoʻohana pinepine ʻia ʻo Astaxanthin i nā huahana mālama ola kino, nā huahana meaʻai meaʻai me ka hopena mālama ola kino a hoʻohui ʻia i nā mea hoʻonani me ka hopena antioxidant.

Manaʻo ʻia e hōʻea ka mākeke astaxanthin honua i $2.55 biliona ma ka makahiki 2025 e like me ka Grand View Research. I kēia manawa, ʻoi aku ka haʻahaʻa o ka hana o ka astaxanthin i loaʻa mai ka synthesis kemika a me Phaffia rhodozyma ma mua o ka levo-astaxanthin kūlohelohe i loaʻa mai ka microalgae ma muli o kāna hana optical structural. ʻO nā levo-astaxanthin kūlohelohe a pau ma ka mākeke mai Haematococcus Pluvialis mai. Eia nō naʻe, ma muli o kona ulu lohi, ka lōʻihi o ka pōʻaiapuni moʻomeheu a me ka maʻalahi o ka hoʻopilikia ʻia e nā mea pili i ke kaiapuni, ua kaupalena ʻia ka hiki ke hana o Haematococcus Pluvialis.

Ma ke ʻano he kumu hou o nā huahana kūlohelohe a me ke keʻena chassis o ka biology synthetic, ʻoi aku ka paʻakikī o ka pūnaewele metabolic a me nā pono biosynthesis o ka microalgae. ʻO Chlamydomonas Reinhardtii ka chassis pattern, i ʻike ʻia ʻo "green yeast". Ua aʻo ʻo PROTOGA i ka ʻenehana hoʻoponopono genetic microalgae holomua a me ka ʻenehana fermentation microalgae downstream. I ka manawa like, ke hoʻomohala nei ʻo PROTOGA i nā ʻenehana photoautotrophic. Ke oʻo ka ʻenehana hoʻoulu a hiki ke hoʻohana ʻia ma ka hana unahi, e hoʻokiʻekiʻe ia i ka pono synthesis e hoʻololi ana i ka CO2 i nā huahana bio-based.