Kupanga kwa Astaxanthin mu Chlamydomonas Reinhardtii

Posachedwapa PROTOGA yalengeza kuti yapanga bwino astaxanthin yachilengedwe mu Chlamydomonas Reinhardtii kudzera mu Microalgae Genetic Modification Platform, ndipo tsopano ikupanga kafukufuku wokhudzana ndi chuma chanzeru komanso kafukufuku wotsatira. Zanenedwa kuti uwu ndi mbadwo wachiwiri wa maselo auinjiniya omwe adayikidwa mu astaxanthin ndipo apitilizabe kusinthasintha. Mbadwo woyamba wa maselo auinjiniya walowa mu gawo loyesera. Kupanga astaxanthin mu Chlamydomonas Reinhardtii popanga mafakitale kungakhale kwabwino kwambiri pamtengo, kupanga ndi khalidwe kuposa Haematococcus Pluvialis.

Astaxanthin ndi xanthophyll yachilengedwe komanso yopangidwa komanso yopanda vitamini A carotenoid, yokhala ndi mphamvu zotsutsana ndi ma antioxidants, zotsutsana ndi kutupa komanso zotsutsana ndi kutupa. Mphamvu yake yolimbana ndi ma antioxidants ndi yoposa nthawi 6000 ya vitamini C komanso yoposa nthawi 550 ya vitamini E. Astaxanthin imagwira ntchito bwino kwambiri poletsa chitetezo chamthupi, kukonza dongosolo la mtima, thanzi la maso ndi ubongo, mphamvu ya khungu, zotsutsana ndi ukalamba ndi ntchito zina. Astaxanthin nthawi zambiri imagwiritsidwa ntchito pazinthu zachipatala, zakudya zopatsa thanzi zomwe zimakhala ndi zotsatira zabwino pa thanzi la thupi komanso imawonjezeredwa mu zodzoladzola zomwe zimakhala ndi mphamvu zotsutsana ndi ma antioxidants.

Msika wapadziko lonse wa astaxanthin ukuyembekezeka kufika $2.55 biliyoni pofika chaka cha 2025 malinga ndi Grand View Research. Pakadali pano, ntchito ya astaxanthin yomwe imapezeka kuchokera ku mankhwala opangidwa ndi Phaffia rhodozyma ndi yotsika kwambiri kuposa ya levo-astaxanthin yachilengedwe yochokera ku microalgae chifukwa cha ntchito yake yowunikira. Levo-astaxanthin yonse yachilengedwe yomwe ili pamsika imachokera ku Haematococcus Pluvialis. Komabe, chifukwa cha kukula kwake pang'onopang'ono, nthawi yayitali yokulira komanso kukhudzidwa mosavuta ndi zinthu zachilengedwe, mphamvu yopanga ya Haematococcus Pluvialis ndi yochepa.

Monga gwero latsopano la zinthu zachilengedwe komanso selo la chassis la biology yopangidwa, microalgae ili ndi maukonde ovuta kwambiri a kagayidwe kachakudya komanso ubwino wa biosynthesis. Chlamydomonas Reinhardtii ndiye chassis ya kapangidwe kake, yomwe imadziwika kuti "yisiti yobiriwira". PROTOGA yakhala ikudziwa bwino ukadaulo wapamwamba wosintha majini a microalgae komanso ukadaulo wotsitsa microalgae fermentation. Nthawi yomweyo, PROTOGA ikupanga ukadaulo wa photoautotrophic. Ukangoyamba kugwiritsa ntchito ukadaulo wobereketsa, udzawonjezera mphamvu ya kapangidwe ka CO2 kukhala zinthu zopangidwa ndi bio.