Kugadzirwa kweAstaxanthin muChlamydomonas Reinhardtii

PROTOGA ichangobva kuzivisa kuti yakabudirira kugadzira astaxanthin yechisikigo muChlamydomonas Reinhardtii kuburikidza neMicroalgae Genetic Modification Platform, uye ikozvino iri kugadzira tsvakurudzo ine chekuita nepfungwa uye tsvakiridzo yekugadzirisa. Zvinonzi ichi chizvarwa chechipiri chemasero einjiniya akaiswa mupayipi yeastaxanthin uye acharamba achichinja. Chizvarwa chekutanga chemasero einjiniya chapinda muchikamu chekuedza kwekutanga. Kugadzirwa kweastaxanthin muChlamydomonas Reinhardtii yekugadzira maindasitiri kwaizova kwakanyanya mumutengo, kubereka uye kunaka kupfuura kweHaematococcus Pluvialis.

Astaxanthin imhando yechisikigo uye yakagadzirwa xanthophyll uye isiri provitamin A carotenoid, ine simba rekudzivirira muviri, kudzivirira kuzvimba uye kudzivirira kupararira kwezvirwere. Basa rayo rekudzivirira muviri rinopetwa ka6000 kupfuura vhitamini C uye ka550 kupfuura vhitamini E. Astaxanthin ine simba rakanaka mukuchengetedza dziviriro yemuviri, kuchengetedza hurongwa hwemwoyo, hutano hwemaziso nehuropi, simba reganda, kudzivirira kukwegura nezvimwe zvinoshandiswa. Astaxanthin inowanzoshandiswa muzvigadzirwa zvehutano, zvigadzirwa zvekudya zvine hutano uye inowedzerwa muzvizoro zvine simba rekudzivirira muviri.

Musika wepasi rose weastaxanthin unotarisirwa kusvika mabhiriyoni emadhora $2.55 panosvika gore ra2025 zvichienderana neGrand View Research. Parizvino, basa reastaxanthin rinowanikwa kubva mukugadzirwa kwemakemikari nePhaffia rhodozyma rakaderera zvikuru pane re natural levo-astaxanthin rinobva mu microalgae nekuda kwebasa rayo re optical. Levo-astaxanthin yese ye natural iri mumusika inobva kuHaematococcus Pluvialis. Zvisinei, nekuda kwekukura kwayo zvishoma nezvishoma, kutenderera kwenguva refu kwekurima uye nyore kukanganiswa nezvinhu zvezvakatipoteredza, kugona kwekugadzira kweHaematococcus Pluvialis kwakaderera.

Senzvimbo itsva yezvigadzirwa zvechisikigo uye sero rechassis re biology yekugadzira, microalgae ine network yakaoma ye metabolic uye zvakanakira biosynthesis. Chlamydomonas Reinhardtii ndiyo chassis yemapatani, inozivikanwa se "yeast yegirini". PROTOGA yakawana tekinoroji yepamusoro yekugadzirisa majini e microalgae uye tekinoroji yekuvirisa microalgae. Panguva imwe chete, PROTOGA iri kugadzira tekinoroji ye photoautotrophic. Kana tekinoroji yekuberekesa yakura uye ikashandiswa pakugadzira scale-production, ichawedzera kushanda kwe synthesis ichishandura CO2 kuita zvigadzirwa zve bio-based.