Kuvumbura Vesicles zo mu bwoko bwa Microalgae Extracellular

Vesicles zo hanze y’ingirabuzimafatizo ni vesicles nini cyane zituruka mu turemangingo, kuva kuri nanometero 30-200 z’umurambararo zitwikiriwe n’ururabo rw’ibinure, rutwara aside nucleic, poroteyine, lipide na metabolites, nibindi. Vesicles zo hanze y’ingirabuzimafatizo ni zo zikoreshwa cyane mu itumanaho hagati y’ingirabuzimafatizo, zigira uruhare mu ihererekanya ry’ibintu hagati y’ingirabuzimafatizo. Vesicles zo hanze y’ingirabuzimafatizo zishobora guturuka mu turemangingo dutandukanye mu bihe bisanzwe kandi by’uburwayi, ahanini bituruka kuri polyvesicles zikozwe n’uduce twa lysosomal two mu ngirabuzimafatizo hanyuma zigasohorwa mu gice cy’inyuma y’ingirabuzimafatizo nyuma yo kwivanga kw’ururabo rw’ingirabuzimafatizo n’ururabo rw’ingirabuzimafatizo za polyvesicles. Kubera ko rufite ubushobozi buke bwo kwirinda indwara, ingaruka mbi zitarimo uburozi, kwibasira cyane, ubushobozi bwo kwambuka umupaka w’amaraso n’ubwonko n’ibindi biranga, byafashwe nk’ibishobora gutwara imiti. Mu 2013, igihembo cya Nobel mu buvuzi n’ubuvuzi cyahawe abahanga batatu bafitanye isano n’ubushakashatsi ku ngirabuzimafatizo zo hanze. Kuva icyo gihe, inzego z’ubushakashatsi n’inganda zatangiye kwiyongera k’ubushakashatsi n’iterambere ry’uturemangingo tw’ingirabuzimafatizo two hanze y’umubiri, ikoreshwa n’ubucuruzi.

Udukoko two hanze y’uturemangingo tw’ibimera dukura mu bice byihariye bikora, duto kandi dushobora kwinjira mu turemangingo. Ibyinshi muri byo bishobora gufatwa no kwinjira mu mara mu buryo butaziguye. Urugero, udukoko twa ginseng dufasha mu gutandukanya uturemangingo tw’ingirabuzimafatizo mu turemangingo tw’imitsi, kandi udukoko twa ginger vesicles dushobora kugenzura ibimera byo mu mara no kugabanya indwara ya colitis. Udukoko duto ni two tumera twa kera cyane dufite uturemangingo tumwe ku Isi. Hari ubwoko hafi 300.000 bw’udukoko duto dukwirakwiriye mu nyanja, mu biyaga, mu migezi, mu butayu, mu misozi miremire, mu birunga n’ahandi, dufite imiterere yihariye mu karere. Mu gihe cy’impinduka z’Isi miliyari 3, udukoko duto twagiye duhora dukura nk’uturemangingo twihariye ku Isi, tudatandukanizwa n’ubushobozi bwatwo budasanzwe bwo gukura no kwisana.

Udukoko two mu bwoko bwa microalgal extracellular vesicles ni ibikoresho bishya by’ubuvuzi bifite umutekano wo hejuru n’ubudahangarwa. Udukoko two mu bwoko bwa microalgae dufite inyungu nyinshi mu gukora udukoko two mu bwoko bwa extracellular vesicles, nko gukora ibintu byoroshye, kugenzurwa, guhenda, gukura vuba, gusohora udukoko twinshi kandi byoroshye gutegurwa. Mu bushakashatsi bwakozwe mbere, uturemangingo two mu bwoko bwa microalgal extracellular vesicles twagaragaye ko tworoshye kwinjiramo n’uturemangingo. Mu nyamaswa, byagaragaye ko twinjizwa mu mara kandi tugakungahaye ku ngingo runaka. Nyuma yo kwinjira muri cytoplasm, dushobora kumara iminsi myinshi, ibyo bikaba ari byo bituma imiti isohoka igihe kirekire.

Byongeye kandi, utunyangingo tw’inkeri duto tw’inkeri duto tw’inkeri twitezweho gushyiramo imiti itandukanye, ituma molekile ziguma neza, zigasohoka buhoro buhoro, zishobora kwihuza n’imiti mu kanwa, n’ibindi, bityo bigakemura imbogamizi zihari mu gutanga imiti. Kubwibyo, iterambere rya molekile duto tw’inkeri duto dufite ubushobozi bwinshi mu guhindura imikorere y’ubuvuzi no mu nganda.