Nchọpụta nke Microalgae Extracellular Vesicles

Vesicles ndị sitere na sel bụ vesicles nano nke dị n'ime sel nke na-ewepụta, site na dayameta 30-200 nm nke kpuchiri na membrane bilayer lipid, nke na-ebu nucleic acids, protein, lipids na metabolites, wdg. Vesicles ndị sitere na sel bụ ngwaọrụ bụ isi nke nkwukọrịta intercellular, nke na-etinye aka na mgbanwe nke ihe dị n'etiti sel. Enwere ike ịpụta vesicles ndị sitere na sel dị iche iche n'okpuru ọnọdụ nkịtị na nke ọrịa, nke sitere na polyvesicles nke mkpụrụ ndụ lysosomal mepụtara ma a na-ahapụ ha n'ime extracellular matrix mgbe ejikọtara ya na extracellular membrane na cell membrane nke polyvesicles. N'ihi obere immunogenicity ya, mmetụta ndị na-adịghị egbu egbu, ebumnuche siri ike, ikike ịgafe ihe mgbochi ọbara-ụbụrụ na njirimara ndị ọzọ, a na-ewere ya dị ka onye nwere ike ibu ọgwụ. Na 2013, enyere ndị ọkà mmụta sayensị atọ metụtara ọmụmụ nke vesicles mpụga onyinye Nobel na Physiology na Medicine. Kemgbe ahụ, ndị ọkà mmụta na ndị ọrụ mmepụta ihe amalitela mmụba nke nnyocha na mmepe nke vesicles ndị dị n'èzí, itinye ha n'ọrụ na ire ahịa ha.

Vesicles sitere na mkpụrụ ndụ ihe nketa nwere ọtụtụ ihe pụrụ iche na-arụ ọrụ, ha pere mpe ma nwee ike ịbanye n'ime anụ ahụ. Ọtụtụ n'ime ha nwere ike iburu ma banye ozugbo n'ime eriri afọ. Dịka ọmụmaatụ, vesicles ginseng na-enyere aka na ọdịiche nke mkpụrụ ndụ ihe nketa ka ọ bụrụ mkpụrụ ndụ akwara, vesicles ginger nwekwara ike ịchịkwa osisi eriri afọ ma belata ọnya afọ. Microalgae bụ osisi kacha ochie nwere otu mkpụrụ ndụ n'ụwa. E nwere ihe fọrọ nke nta ka ọ bụrụ ụdị microalgae 300,000 nke a na-ekesa nke ọma n'oké osimiri, ọdọ mmiri, osimiri, ọzara, ala dị larịị, glaciers na ebe ndị ọzọ, nwere njirimara mpaghara pụrụ iche. N'oge mgbanwe nke ụwa ijeri atọ, microalgae enweela ike itolite dị ka mkpụrụ ndụ otu n'ụwa, nke na-enweghị ikewapụ na uto pụrụ iche ha na ikike idozi onwe ha.

Vesicles nke microalgal extracellular bụ ihe ọhụrụ na-arụ ọrụ biomedical nwere nchekwa na nkwụsi ike dị elu. Microalgae nwere ọtụtụ uru na mmepụta nke vesicles nke extracellular, dị ka usoro ọdịbendị dị mfe, nke a na-achịkwa, nke dị ọnụ ala, uto ngwa ngwa, mmepụta dị elu nke vesicles na mfe imepụta. Na ọmụmụ ihe ndị gara aga, achọpụtara na mkpụrụ ndụ na-abanye n'ime microalgal extracellular vesicles ngwa ngwa. Na ụdị anụmanụ, achọpụtara na ha na-abanye ozugbo site na eriri afọ ma na-eme ka ha baa ọgaranya na anụ ahụ ụfọdụ. Mgbe ha banyere na cytoplasm, ọ nwere ike ịdịru ọtụtụ ụbọchị, nke na-eme ka mwepụta ọgwụ na-adịgide adịgide ruo ogologo oge.

Tinyere nke a, a na-atụ anya na microalgal extracellular vesicles ga-ebu ọtụtụ ọgwụ dị iche iche, nke na-eme ka molekul kwụsie ike, mwepụta ngwa ngwa, ime mgbanwe ọnụ, wdg, na-edozi ihe mgbochi nchịkwa ọgwụ dị ugbu a. Ya mere, mmepe nke microalgae extracellular vesicles nwere nnukwu ohere na mgbanwe ahụike na mmepụta ụlọ ọrụ.