Ka ʻike ʻana o nā Microalgae Extracellular Vesicles

ʻO nā vesicles Extracellular he mau vesicles nano-size endogenous i hūnā ʻia e nā cell, mai 30-200 nm ke anawaena i hoʻopuni ʻia i loko o kahi membrane lipid bilayer, kahi e lawe ai i nā nucleic acid, nā protein, lipids a me nā metabolites, a pēlā aku. ʻO nā vesicles Extracellular nā mea hana nui o ka kamaʻilio intercellular, e pili ana i ka hoʻololi ʻana o nā mea ma waena o nā cell. Hiki ke hūnā ʻia nā vesicles Extracellular e nā ʻano cell like ʻole ma lalo o nā kūlana maʻamau a me nā kūlana pathological, ka mea nui i loaʻa mai nā polyvesicles i hana ʻia e nā ʻāpana lysosomal intracellular a hoʻokuʻu ʻia i loko o ka matrix extracellular ma hope o ka hui ʻana o ka membrane extracellular a me ka membrane cell o nā polyvesicles. Ma muli o kona immunogenicity haʻahaʻa, nā hopena ʻaoʻao ʻaʻohe ʻawaʻawa, ka hoʻopaʻa ikaika ʻana, ka hiki ke hele i ka pale koko-lolo a me nā ʻano ʻē aʻe, ua manaʻo ʻia he mea lawe lāʻau lapaʻau. I ka makahiki 2013, ua hāʻawi ʻia ka Nobel Prize ma Physiology and Medicine i ʻekolu mau kānaka ʻepekema e pili ana i ke aʻo ʻana i nā vesicles waho. Mai ia manawa, ua hoʻomaka nā pōʻai hoʻonaʻauao a me nā ʻoihana i ka piʻi ʻana o ka noiʻi a me ka hoʻomohala ʻana, ka hoʻohana ʻana a me ke kālepa ʻana i nā vesicles extracellular.

Waiwai nā vesicles extracellular mai nā cell mea kanu i nā ʻāpana hana kūikawā, liʻiliʻi ka nui a hiki ke komo i nā ʻiʻo. Hiki ke lawe ʻia ka hapa nui o lākou a komo pololei i loko o ka ʻōpū. No ka laʻana, kōkua nā vesicles ginseng i ka hoʻokaʻawale ʻana o nā cell kumu i nā cell nerve, a hiki i nā vesicles ginger ke hoʻoponopono i nā flora ʻōpū a hōʻoluʻolu i ka colitis. ʻO Microalgae nā mea kanu cell hoʻokahi kahiko loa ma ka Honua. Aia ma kahi o 300,000 mau ʻano microalgae i hoʻolaha nui ʻia ma nā moana, nā loko, nā muliwai, nā wao nahele, nā plateaus, nā glaciers a me nā wahi ʻē aʻe, me nā ʻano ʻāpana kū hoʻokahi. I ka wā o ka ulu ʻana o ka Honua 3 biliona, ua hiki mau i nā microalgae ke ulu ma ke ʻano he mau cell hoʻokahi ma ka Honua, kahi mea hiki ʻole ke hoʻokaʻawale ʻia mai ko lākou ulu kupaianaha a me ka hiki ke hoʻoponopono iā lākou iho.

ʻO nā vesicles extracellular microalgal he mau mea hana biomedical hou me ka palekana kiʻekiʻe a me ke kūpaʻa. He nui nā pono o Microalgae i ka hana ʻana i nā vesicles extracellular, e like me ke kaʻina hana maʻalahi, hiki ke hoʻomalu ʻia, makepono ke kumu kūʻai, ulu wikiwiki, ka hana kiʻekiʻe o nā vesicles a maʻalahi hoʻi e hana ʻia. I nā haʻawina i hala, ua ʻike ʻia nā vesicles extracellular microalgal e maʻalahi ke komo ʻia e nā cell. I nā hiʻohiʻona holoholona, ​​​​ua ʻike ʻia ua komo pololei lākou ma o ka ʻōpū a hoʻonui ʻia i loko o nā ʻiʻo kikoʻī. Ma hope o ke komo ʻana i ka cytoplasm, hiki ke mau no kekahi mau lā, kahi mea e kōkua ai i ka hoʻokuʻu ʻana i ka lāʻau lapaʻau no ka manawa lōʻihi.

Eia kekahi, manaʻo ʻia nā vesicles extracellular microalgal e hoʻouka i nā ʻano lāʻau like ʻole, e hoʻomaikaʻi ana i ke kūpaʻa o nā molekala, ka hoʻokuʻu lohi, ka hoʻololi waha, a me nā mea ʻē aʻe, e hoʻoponopono ana i nā pilikia o ka hoʻokele lāʻau lapaʻau e kū nei. No laila, ʻo ka hoʻomohala ʻana o nā vesicles extracellular microalgae he kiʻekiʻe ka hiki ke hana i ka hoʻololi lapaʻau a me ka ʻoihana.